Charles River

Charles River旗下的Retrogenix细胞微阵列能够发现原代细胞表面受体以及潜在的脱靶细胞。经过10多年的扩展和完善,我们的细胞微阵列库现在有超过6500种蛋白质用于筛选,包括高于98%的怀孕8-10周的产前蛋白质。利用最大的市售质膜和人类细胞中表达的分泌蛋白,发现高质量、可开发的药物靶点和作用机制。该技术可用于多种生物制剂,包括抗体、蛋白质、小分子、病毒、CAR疗法和其他配体。结合抗体和细胞治疗开发平台的全面组合,Charles River可以加速您的药物开发管道,从候选药物选择到安全性评估等。

The Retrogenix Cell Microarray enables the discovery of primary cell surface receptors as well as potential off-targets. With over 10 years of expansion and refinement, our cell microarray libraries now have over 6,500 proteins for screening, including >98% of prenatal proteins present at 8-10 weeks of pregnancy. Discover high quality, exploitable drug targets and mechanisms of action using the largest commercially available set of plasma membrane and secreted proteins expressed in human cells. The technology can be used with a wide variety of biologics including antibodies, proteins, small molecules, viruses, CAR therapeutics, and other ligands. Together with an exhaustive portfolio for antibody and cellular therapeutic development platforms, Charles River can accelerate your drug development pipelines from candidate selection to safety assessment and beyond.

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