Artios Pharma 致力于通过基于癌细胞利用DNA损伤修复(DDR)反应来促进其生存，从而治愈癌症。我们的专业DcoDeR平台整合了Artios在DNA损伤生物学和药物发现方面的领导能力、专业知识和经验，系统地发现和开发针对DDR全过程的药物。Artios建立了大覆盖面的以DDR为重点的产品管线，旨在解决实体瘤适应症中还未实现解决方案的重点需求领域。Artios的主要产品是ATR抑制剂ART0380和Polθ抑制剂ART4215，这两种药物目前都处于临床1 / 2期，分别作为单一疗法和联合疗法开发。Artios与默克公司和诺华公司建立了世界级的战略合作伙伴关系，并与英国癌症研究中心、癌症研究所、荷兰癌症研究所和弗朗西斯·克里克研究所等一流机构开展了研究合作，共同开创了DDR药物研发的有效方法。

Artios Pharma is on a mission to kill cancer by exploiting DNA damage repair (DDR) responses that are leveraged by cancer cells to promote their survival. Its specialized DcoDeR platform integrates Artios’ leadership capabilities, expertise and experience in DNA damage biology and drug discovery to systematically discover and develop medicines targeting the totality of the DDR. Artios has built an extensive DDR focused pipeline designed to address areas of high unmet needs across solid tumour indications. Its lead programs are our ATR inhibitor, ART0380, and our Polθ inhibitor, ART4215, both currently in Phase 1 / 2 develop as monotherapy and with combination treatments. Together with its world-class strategic partnerships with Merck KGaA and Novartis, and research collaborations with premiere institutions like Cancer Research UK, The Institute of Cancer Research, The Netherlands Cancer Institute, and the Crick Institute we are pioneering validated approaches to DDR drug discovery.