科瑞思特（Crystec）是一家英国高科技公司，掌握全球最先进的超临界流体结晶产业化平台技术(mSAS®)，一种高效、稳定，可放大的药物递送技术，并得到了药监部门的认可。该技术应用面广，适用于小分子化学药和大分子生物药，通过优化各种药物剂型（例如吸入,口服，鼻内，皮下，舌下），增强体内给药效率，提高临床疗效。公司创始人于九十年代中期在全球率先将超临界结晶技术应用于药物结晶和微粒设计领域，并带领团队发明了一系列工艺专利，成为全球公认的该领域领军人。科瑞思特建立了完整的超临界结晶技术（mSAS®)产业化设施和工艺开发能力，包括小试，中试到cGMP生产。同时，该公司根据临床需求及其技术优势，在某些重要领域开发了一系列自主创新产品管线，包括妇女健康，偏头痛，呼吸疾病，感染类等领域。科瑞思特的技术平台得到了中英两国政府的支持，公司先后获得英国科技部资助的高端生产技术链奖，创新部技术创新奖，和中英联合资助的中英牛顿基金奖，以及欧洲CPHI药物制剂和合同服务外包卓越奖。
科瑞思特（Crystec）与全球许多医药企业建立了合作，为他们提供优化的制剂解决方案，开发差异化产品。利用mSAS®平台技术的独特能力，开发更高质量（例如，提高药物稳定性和产品批次间一致性），更直接的给药靶点（例如，准确的局部给药），和更方便的使用（例如，吸入给药代替针剂），以提高临床疗效（例如，提高生物利用度和快速起效）,造福患者。
CrystecPharma is a crystal and particle engineering company applying proprietary modified supercritical fluid (SCF) technologies to improve the performance of medicines. The technology enables drug molecules to be crystallised in new forms and novel particles to be manufactured in ways that greatly enhance their therapeutic performance. Crystec has an enabling platform which can be applied to small and large molecules, to optimise a range of medicine dosage forms (e.g. oral, inhaled, intranasal, subcutaneous, sublingual).
Crystec works with the global pharmaceutical and health care industry to solve drug particle formation, formulation and process challenges. They are also developing their own innovative therapies in important areas of unmet clinical need, including women’s health, urology and treating respiratory disease. Crystec’s proprietary ‘mSAS®’ (modified Supercritical Anti-Solvent) drug delivery technology is enabled by a highly efficient, stable and fully scalable manufacturing process and is approved by regulatory authorities. This award winning mSAS® platform creates unique opportunities to improve medicines in ways that can transform the quality of life for many patients.
The Crystec team is multi-disciplinary with extensive experience in pharmaceutical development. The team have pioneered the application of SCF to pharmaceuticals and consists of acknowledged leaders in relevant fields of science, drug delivery, engineering, scale-up, manufacturing and medicine, underpinned by senior-level pharmaceutical industry and licensing experience.